Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459272 | 0.89 | HTR7 (0.51) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL7283000 | 0.84 | KDM4E (0.45) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL15522001 | 0.83 | TP53 (0.71) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL13740267 | 0.83 | TP53 (0.71) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL19806810 | 0.83 | HTT (0.51) | KDM4ELMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL28658769 | 0.81 | HTR7 (0.57) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL13739614 | 0.81 | TP53 (0.69) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL13739595 | 0.81 | TP53 (0.74) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL9228166 | 0.81 | ADRB2 (0.55) | HTR7TP53MAPK1RAB9AADRB2 | |
| SCHEMBL10526915 | 0.81 | ADRB2 (0.54) | HTR7TP53MAPK1RAB9AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |