Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275541 | 0.85 | METAP1 (0.39) | ALDH1A1BMP1HPGDSMN1; SMN2USP2 | |
| SCHEMBL7275547 | 0.85 | METAP1 (0.39) | ALDH1A1BMP1HPGDSMN1; SMN2USP2 | |
| SCHEMBL7293215 | 0.85 | METAP1 (0.39) | ALDH1A1BMP1HPGDSMN1; SMN2USP2 | |
| SCHEMBL7269423 | 0.76 | METAP2 (0.45) | HPGDSMN1; SMN2KDM4EMETAP1 | |
| SCHEMBL7269419 | 0.76 | METAP2 (0.45) | HPGDSMN1; SMN2KDM4EMETAP1 | |
| SCHEMBL7269427 | 0.76 | METAP2 (0.45) | HPGDSMN1; SMN2KDM4EMETAP1 | |
| SCHEMBL7269414 | 0.76 | METAP2 (0.45) | HPGDSMN1; SMN2KDM4EMETAP1 | |
| SCHEMBL7282960 | 0.74 | METAP2 (0.43) | HPGDSMN1; SMN2KDM4EMETAP1 | |
| SCHEMBL11151822 | 0.70 | KMT2A (0.58) | ALDH1A1HPGDUSP2KDM4EPOLB | |
| SCHEMBL15272327 | 0.70 | KMT2A (0.58) | ALDH1A1HPGDUSP2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332008-A2 | Peptide-like aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |