Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 3/20 | 0.46 |
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284683 | 0.87 | CYP1A2 (0.59) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL6692156 | 0.82 | CLEC4M (0.67) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL7290898 | 0.82 | CYP1A2 (0.60) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL4906659 | 0.81 | GABRA1 (0.71) | GABRA1GABRB2GABRA3GABRB1ALDH1A1 | |
| SCHEMBL20604985 | 0.81 | MEN1 (0.51) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL10493397 | 0.81 | CLEC4M (0.56) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL4176704 | 0.79 | MDH2 (0.76) | GABRA1GABRB2GABRA3GABRB1ALDH1A1 | |
| SCHEMBL774558 | 0.77 | CLEC4M (0.76) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL5161582 | 0.76 | GABRA1 (0.64) | GABRA1GABRB2GABRA3GABRB1CLEC4M | |
| SCHEMBL17424066 | 0.76 | CYP1A2 (0.59) | GABRA1GABRB2GABRA3GABRB1CLEC4M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |