Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276696 | 0.90 | ALDH1A1 (0.44) | KMT2AL3MBTL1CYP1A2PPARAALDH1A1 | |
| SCHEMBL7282625 | 0.90 | EPHX2 (0.47) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7324725 | 0.87 | EPHX2 (0.49) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL9800576 | 0.81 | EPHX2 (0.50) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL9800573 | 0.81 | EPHX2 (0.50) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7141356 | 0.81 | EPHX2 (0.51) | EPHX2PPARGMMP8MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL7420885 | 0.80 | EPHX2 (0.50) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7332824 | 0.80 | PPARG (0.52) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7385299 | 0.80 | ALDH1A1 (0.43) | KMT2AL3MBTL1CYP1A2PPARAALDH1A1 | |
| SCHEMBL9261571 | 0.79 | SMN1; SMN2 (0.44) | EPHX2PPARGMMP8MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |