Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800576 | 1.00 | EPHX2 (0.50) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7324725 | 0.86 | EPHX2 (0.49) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7282625 | 0.84 | EPHX2 (0.47) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7283182 | 0.81 | EPHX2 (0.46) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7332824 | 0.79 | PPARG (0.52) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7562347 | 0.78 | HK1 (0.39) | EPHX2PPARGMMP8POLB | |
| SCHEMBL7141356 | 0.78 | EPHX2 (0.51) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7436917 | 0.78 | PPARG (0.51) | EPHX2PPARGMMP8PPARAMEN1 | |
| SCHEMBL7486719 | 0.78 | CYP1A2 (0.42) | PPARAKMT2APOLBALDH1A1 | |
| SCHEMBL10521821 | 0.77 | MMP8 (0.61) | EPHX2PPARGMMP8PPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |