Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950866 | 0.89 | KDM4E (0.44) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL14420588 | 0.89 | KDM4E (0.44) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL2385238 | 0.83 | CYP17A1 (0.50) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL17414701 | 0.83 | CYP17A1 (0.50) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL28434333 | 0.82 | KDM4E (0.40) | KDM4EKMT2ACYP19A1CYP17A1 | |
| Hydrochloric Acid SCHEMBL29139305 | 0.81 | CYP17A1 (0.49) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL28185835 | 0.81 | KDM4E (0.46) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL2398555 | 0.81 | TBXAS1 (0.46) | KDM4EKMT2ACYP19A1CYP17A1 | |
| Bromide SCHEMBL28331929 | 0.81 | CYP17A1 (0.49) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL11871891 | 0.81 | TBXAS1 (0.46) | KDM4EKMT2ACYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230035-B1 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID CO (US) | 1994-10-12 | — | — | EP | disclosed |
| US-4728663-A | HYPOTENSIVE, ANTIARRHYTHMIA | AMERICAN CYANAMID COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |