Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385238 | 1.00 | CYP17A1 (0.50) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL29139305 | 0.98 | CYP17A1 (0.49) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| Bromide SCHEMBL28331929 | 0.98 | CYP17A1 (0.49) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| SCHEMBL11871891 | 0.94 | TBXAS1 (0.46) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| SCHEMBL2398555 | 0.94 | TBXAS1 (0.46) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL2414285 | 0.93 | CYP17A1 (0.44) | CYP17A1KDM4ETBXAS1KMT2ACYP19A1 | |
| SCHEMBL10456414 | 0.93 | TBXAS1 (0.49) | CYP17A1KDM4ETBXAS1KMT2A | |
| SCHEMBL16163817 | 0.93 | TBXAS1 (0.49) | CYP17A1KDM4ETBXAS1KMT2A | |
| SCHEMBL16163925 | 0.93 | TBXAS1 (0.49) | CYP17A1KDM4ETBXAS1KMT2A | |
| SCHEMBL5086764 | 0.93 | TBXAS1 (0.49) | CYP17A1KDM4ETBXAS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002159-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | ZONDLO NEAL (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002159-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | FIBP, HDGF, PLOD3 | CYP17A1 2299/4885KDM4E 2710/4885TBXAS1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.