Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569673 | 0.90 | HDAC3 (0.37) | FFAR1 | |
| SCHEMBL11254152 | 0.77 | KEAP1 (0.36) | KEAP1FFAR1NPSR1 | |
| SCHEMBL7413999 | 0.71 | ALDH1A1 (0.33) | KEAP1FFAR1NPSR1 | |
| SCHEMBL18283317 | 0.68 | — | — | |
| SCHEMBL238692 | 0.68 | — | — | |
| SCHEMBL6883456 | 0.67 | HDAC3 (0.40) | FFAR1 | |
| SCHEMBL2147545 | 0.66 | — | — | |
| SCHEMBL10464808 | 0.65 | — | — | |
| Glycine SCHEMBL6884148 | 0.62 | HDAC3 (0.36) | FFAR1NPSR1 | |
| SCHEMBL11727178 | 0.62 | KEAP1 (0.33) | KEAP1FFAR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330241-A2 | Calcitonin derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |