Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284983 | 0.94 | ITGB3 (0.58) | ITGB3ITGA2BKMT2AIRAK4MAPT | |
| Lefradafiban SCHEMBL7080546 | 0.94 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4KDM4EMAPT | |
| Lefradafiban SCHEMBL50399 | 0.94 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4KDM4EMAPT | |
| SCHEMBL7304724 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BKMT2AIRAK4KDM4E | |
| SCHEMBL7281873 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BIRAK4KDM4EFFAR4 | |
| SCHEMBL7284195 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BKMT2AIRAK4KDM4E | |
| SCHEMBL7302804 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4KDM4EHRH3 | |
| SCHEMBL7304269 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4KDM4E | |
| SCHEMBL7275650 | 0.87 | ITGB3 (0.63) | ITGB3ITGA2BIRAK4KDM4EMAPT | |
| SCHEMBL7308125 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BKMT2AIRAK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |