Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285147 | 0.93 | ITGB3 (0.49) | ITGB3ITGA2BMASP2FFAR4IRAK4 | |
| Lefradafiban SCHEMBL50399 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BMASP2FFAR4IRAK4 | |
| Lefradafiban SCHEMBL7080546 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BMASP2FFAR4IRAK4 | |
| SCHEMBL7284195 | 0.91 | ITGB3 (0.57) | ITGB3ITGA2BMASP2IRAK4KDM4E | |
| SCHEMBL7302804 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4KDM4EHRH3 | |
| SCHEMBL7283791 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BFFAR4IRAK4KDM4E | |
| SCHEMBL7312569 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BMASP2FFAR4IRAK4 | |
| SCHEMBL7304269 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4KDM4ELTA4H | |
| SCHEMBL7282413 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BMASP2IRAK4 | |
| SCHEMBL7304690 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |