Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285777 | 0.87 | PTPN7 (0.51) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL7293649 | 0.83 | PTPN7 (0.51) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL7294266 | 0.79 | POLB (0.54) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7285630 | 0.77 | ALOX15 (0.47) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL28124598 | 0.77 | PTGDR2 (0.64) | PTPN7TSHRALOX15FFAR1PTGDR2 | |
| SCHEMBL5384662 | 0.76 | MCL1 (0.63) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL5395902 | 0.76 | MCL1 (0.68) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL13665126 | 0.75 | NPC1 (0.59) | HSD17B10LMNAMAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL5394389 | 0.75 | TSHR (0.71) | PTPN7TSHRALOX15HSD17B10MCL1 | |
| SCHEMBL7173279 | 0.75 | TSHR (0.62) | PTPN7TSHRALOX15HSD17B10MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |