Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284280 | 0.84 | KDM4E (0.50) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL7285180 | 0.82 | LMNA (0.55) | POLBKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL7284352 | 0.80 | KDM4E (0.53) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL7294269 | 0.80 | LMNA (0.54) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL7284147 | 0.79 | PTPN7 (0.51) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3046274 | 0.78 | POLB (0.68) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL8436924 | 0.77 | MAOB (0.55) | POLBMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8681578 | 0.77 | ALDH1A1 (0.61) | POLBKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL7284282 | 0.76 | KDM4E (0.50) | POLBKDM4ELMNAMEN1KMT2A | |
| SCHEMBL8013977 | 0.76 | ALOX15 (0.61) | POLBKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |