⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450724 | 0.90 | POLB (0.31) | — | |
| SCHEMBL8639716 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL448902 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL8639878 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL28156149 | 0.77 | IDO1 (0.35) | — | |
| SCHEMBL728463 | 0.77 | — | — | |
| SCHEMBL11736693 | 0.77 | — | — | |
| SCHEMBL728477 | 0.76 | FOLH1 (0.34) | — | |
| SCHEMBL29520127 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL331176 | 0.75 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | claimed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | claimed |
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8138297-B2 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | disclosed |