Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639878 | 0.95 | ALDH1A1 (0.32) | ALDH1A1KDM4EMAPK1SMN1; SMN2TSHR | |
| SCHEMBL29520127 | 0.88 | ALDH1A1 (0.33) | ALDH1A1MAPK1TSHRLTA4H | |
| SCHEMBL331176 | 0.88 | ALDH1A1 (0.33) | ALDH1A1MAPK1TSHRLTA4H | |
| SCHEMBL28264117 | 0.86 | TSHR (0.30) | TSHR | |
| SCHEMBL728441 | 0.86 | — | — | |
| Benzene SCHEMBL28867986 | 0.86 | LTA4H (0.37) | ALDH1A1KDM4EMAPK1SMN1; SMN2TSHR | |
| SCHEMBL28172908 | 0.83 | HPGD (0.37) | ALDH1A1KDM4EMAPK1SMN1; SMN2TSHR | |
| SCHEMBL28156149 | 0.82 | IDO1 (0.35) | ALDH1A1KDM4ETSHR | |
| SCHEMBL728477 | 0.80 | FOLH1 (0.34) | — | |
| SCHEMBL1225533 | 0.80 | TSHR (0.33) | ALDH1A1KDM4EMAPK1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641820-B1 | Organosilicon polymer and process for the preparation thereof | TOSHIBA SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5489662-A | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0641820-A1 | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |