Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294840 | 0.93 | TDP1 (0.44) | L3MBTL1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL7294020 | 0.84 | AAK1 (0.41) | ALDH1A1MAPTHPGDCYP3A4KDM4E | |
| SCHEMBL7292041 | 0.83 | KDM4E (0.51) | L3MBTL1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL7284949 | 0.82 | AAK1 (0.40) | ALDH1A1MAPTHPGDCYP3A4CYP2D6 | |
| SCHEMBL7284759 | 0.78 | AAK1 (0.42) | L3MBTL1ALDH1A1TDP1CYP3A4CYP11B1 | |
| SCHEMBL7291149 | 0.78 | AAK1 (0.43) | L3MBTL1ALDH1A1TDP1CYP3A4CYP11B1 | |
| SCHEMBL7285326 | 0.78 | AAK1 (0.41) | KMT2AALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7282598 | 0.77 | KDM4E (0.44) | L3MBTL1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL25009811 | 0.76 | L3MBTL1 (0.82) | L3MBTL1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL7306378 | 0.75 | AAK1 (0.45) | L3MBTL1ALDH1A1HPGDTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200024-B1 | 3-CYANO-PYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0200024-A2 | 3-Cyano-pyridines, process for their preparation and their pharmaceutical use | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |