Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351046 | 0.98 | NAAA (0.41) | NAAAPRCPEPHX1TSHRTLR2 | |
| SCHEMBL25590375 | 0.95 | ALDH1A1 (0.39) | NAAAPRCPTSHRTLR2 | |
| SCHEMBL629326 | 0.78 | PRCP (0.54) | NAAAPRCPEPHX1TLR2 | |
| SCHEMBL629327 | 0.78 | PRCP (0.54) | NAAAPRCPEPHX1TLR2 | |
| SCHEMBL7228241 | 0.77 | NAAA (0.46) | NAAA | |
| SCHEMBL11881200 | 0.77 | NAAA (0.50) | NAAAEPHX1TSHRPPARG | |
| SCHEMBL9658685 | 0.77 | PRCP (0.56) | NAAAPRCPEPHX1TSHRTLR2 | |
| SCHEMBL7782934 | 0.77 | PRCP (0.56) | NAAAPRCPEPHX1TSHRTLR2 | |
| SCHEMBL7780475 | 0.77 | PRCP (0.56) | NAAAPRCPEPHX1TSHRTLR2 | |
| SCHEMBL7533568 | 0.77 | PRCP (0.56) | NAAAPRCPEPHX1TSHRTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| CN-1091288-A | The oxytocin antagonist | OTSUKA PHARMA CO LTD (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |