Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.82 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.82 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382276 | 1.00 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| Lamifiban SCHEMBL4683 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| Lamifiban SCHEMBL871446 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| SCHEMBL7283671 | 0.90 | ITGB3 (0.67) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL8377721 | 0.90 | ITGB3 (0.67) | ITGB3ITGA2BCYP51A1CA2KMT2A | |
| SCHEMBL8383693 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| SCHEMBL8383686 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| SCHEMBL8383672 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| SCHEMBL8383680 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2BCYP51A1CA1CA2 | |
| SCHEMBL8379660 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BCYP51A1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | disclosed |
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0656348-A2 | Aceric acid derivatives as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-07 | — | — | EP | disclosed |