Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.74 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377742 | 0.87 | ITGB3 (0.70) | ITGB3ITGA2BMBOAT4 | |
| SCHEMBL7296779 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BMBOAT4MEN1KMT2A | |
| Sibrafiban SCHEMBL50759 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2BF2SMYD3LMNA | |
| Sibrafiban SCHEMBL27618015 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2BF2SMYD3LMNA | |
| SCHEMBL8645304 | 0.81 | ITGB3 (0.73) | ITGB3ITGA2BKMT2ASMYD3LMNA | |
| SCHEMBL4434863 | 0.80 | ITGB3 (0.71) | ITGB3ITGA2BSMYD3 | |
| SCHEMBL5144245 | 0.80 | ITGB3 (0.71) | ITGB3ITGA2BSMYD3 | |
| SCHEMBL8649064 | 0.80 | ITGB3 (0.71) | ITGB3ITGA2BSMYD3 | |
| SCHEMBL27403694 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BF2SMYD3 | |
| SCHEMBL27544859 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BF2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | disclosed |
| EP-0656348-A2 | Aceric acid derivatives as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-07 | — | — | EP | disclosed |