SCHEMBL728482

SCHEMBL728482

CCO[SiH](OCC)OCCCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728354 0.93 HDAC3 (0.30)
SCHEMBL730273 0.91 HDAC3 (0.33)
SCHEMBL729781 0.91 HDAC3 (0.33)
SCHEMBL729814 0.91 HDAC3 (0.33)
SCHEMBL3155337 0.85
SCHEMBL11788878 0.80 TSHR (0.33)
SCHEMBL931736 0.79 ADRB2 (0.39)
SCHEMBL5346538 0.79 ADRB2 (0.39)
1-Propanethiol SCHEMBL23748566 0.78
SCHEMBL3149962 0.78 HDAC3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
CN-115667453-A Hydrophilizing agent 日涂表面处理化工有限公司 2023-01-31 CN disclosed
CN-113924334-A Silane coupling agent composition comprising silane compound and protein denaturing agent, and rubber composition comprising same 引能仕株式会社 2022-01-11 CN disclosed
CN-113490606-A Sulfur-containing silane compounds and compositions thereof 引能仕株式会社 2021-10-08 CN disclosed
US-9434858-B2 Hydrophilic coating agent OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-09-06 US disclosed
US-20150259570-A1 HYDROPHILIC COATING AGENT OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2015-09-17 US disclosed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
EP-2292451-B1 RUN-FLAT TIRE BRIDGESTONE CORP (JP) 2012-11-07 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20110083780-A1 RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2011-04-14 US disclosed
EP-2292451-A1 RUN-FLAT TIRE Bridgestone Corporation (JP) 2011-03-09 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed