SCHEMBL931736

SCHEMBL931736

CCCCO[SiH](OCC)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
TSHR P16473 4/20 0.35
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5346538 1.00 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL3871723 0.95 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
Methylamine SCHEMBL201624 0.95 ADRB2 (0.42) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608608 0.92 THRB (0.35) TSHRALDH1A1CA1CA2THRB
SCHEMBL3321056 0.92 THRB (0.35) TSHRALDH1A1CA1CA2THRB
SCHEMBL310148 0.91 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL17391451 0.90 THRB (0.40) TSHRALDH1A1CA1CA2THRB
SCHEMBL4429193 0.90 THRB (0.40) TSHRALDH1A1CA1CA2THRB
SCHEMBL28719230 0.90 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL17391430 0.90 THRB (0.40) TSHRALDH1A1CA1CA2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP claimed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US claimed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US claimed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP claimed
US-9657039-B2 Production method for alkoxysilanes NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-05-23 US disclosed
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-01-07 US disclosed
EP-2872461-A2 POWDER MIXTURE AND PROCESS TO MAKE DRY MORTAR Akzo Nobel Chemicals International B.V. (NL) 2015-05-20 EP disclosed
WO-2014009299-A2 POWDER MIXTURE AND PROCESS TO MAKE DRY MORTAR AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2014-01-16 WO disclosed
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP disclosed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US disclosed
CN-102212196-B Coupled copolymer and method for producing the same TSRC CORP 2013-03-06 CN disclosed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US disclosed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP disclosed
EP-0691362-B1 Method of producing organopolysiloxanes containing hydrolyzable functional groups, and curable resin composition using said organopolysiloxanes SHINETSU CHEMICAL CO (JP) 2000-10-25 EP disclosed
US-5633311-A ROOM TEMPERATURE CURABLE RESIN SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-05-27 US disclosed
EP-0691362-A2 Method of producing organopolysiloxanes containing hydrolyzable functional groups, and curable resin composition using said organopolysiloxanes Shin-Etsu Chemical Co., Ltd. (JP) 1996-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES MSMO1, MGAM, MACO1 ADRB2 3721/4885ADRB1 3712/4885ADRB3 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.