Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.60 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828325 | 0.88 | CARM1 (0.64) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL1088446 | 0.87 | SIGMAR1 (0.74) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL7225346 | 0.85 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| Hydrochloric Acid SCHEMBL1087168 | 0.85 | SIGMAR1 (0.71) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL29733117 | 0.85 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL7055109 | 0.83 | CARM1 (0.75) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL20460230 | 0.82 | SIGMAR1 (0.68) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL2949711 | 0.82 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL12359495 | 0.82 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL1638713 | 0.82 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |
| EP-0370236-B1 | INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
| EP-0370236-A1 | Indolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0362695-A1 | Pyrrolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| US-5516915-A | Bis-(1H-indol-3-yl)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| US-5508403-A | ENHANCES EFFECTS OF ANTITUMOR AGENTS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0353692-B1 | Drug effect-enhancing agent for antitumor drug | NISSAN CHEMICAL IND LTD (JP) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |
| US-5438050-A | Indolocarbazole derivatives, processes for their preparation and compositions containing them | GODECKE AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| US-5304550-A | Synergistic | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5130303-A | Pyridine derivative administering | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0370236-B1 | INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | disclosed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0353692-A2 | Drug effect-enhancing agent for antitumor drug | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |