Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281873 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BIRAK4NR1H4MASP2 | |
| SCHEMBL7276046 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BIRAK4KDM4E | |
| Lefradafiban SCHEMBL7080546 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4MASP2FFAR4 | |
| Lefradafiban SCHEMBL50399 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4MASP2FFAR4 | |
| SCHEMBL7337066 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4CSNK2A2CSNK2A1 | |
| SCHEMBL7285055 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4CSNK2A2CSNK2A1 | |
| SCHEMBL7284195 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BIRAK4MASP2KDM4E | |
| Hydrochloric Acid SCHEMBL7278229 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BIRAK4KDM4E | |
| SCHEMBL7302804 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4KDM4E | |
| SCHEMBL7312569 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BIRAK4MASP2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |