SCHEMBL7285160

SCHEMBL7285160

CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.61
CTSS P25774 2/20 0.61
PSENEN Q9NZ42 1/20 0.50
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.46
CA7 P43166 1/20 0.46
PREP P48147 1/20 0.44
TRPA1 O75762 1/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17596020 1.00 CTSK (0.61) CTSKCTSSPSENENCA2CA1
SCHEMBL18562066 1.00 CTSK (0.61) CTSKCTSSPSENENCA2CA1
SCHEMBL25015110 1.00 CTSK (0.61) CTSKCTSSPSENENCA2CA1
SCHEMBL15671593 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL22371979 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL3087516 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL22371978 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL22371977 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL7345607 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL7018649 0.88 CTSK (0.63) CTSKCTSSPSENENCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029214-A Phospholipid drug conjugate and preparation method and application thereof 上海弼领生物技术有限公司 2026-05-12 CN disclosed
EP-4721767-A1 ANTI-B7-H3 ANTIBODY OR FRAGMENT THEREOF, AND ANTIBODY DRUG CONJUGATE TARGETING B7-H3 Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. (CN) 2026-04-08 EP disclosed
US-12589101-B2 Cyclodextrin protein drug conjugates REGENERON PHARMACEUTICALS, INC. (US) 2026-03-31 US disclosed
US-20260053943-A1 NANOCOMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE AND USE THEREOF FULGENT GENETICS INC (US) 2026-02-26 US disclosed
EP-4673474-A2 ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2026-01-07 EP disclosed
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
EP-4656248-A2 ANTI-C-MET ANTIBODY DRUG CONJUGATES AbbVie Manufacturing Management Unlimited Company (IE) 2025-12-03 EP disclosed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP disclosed
EP-4217398-B1 ANTI-C-MET ANTIBODY DRUG CONJUGATES ABBVIE MFG MANAGEMENT UNLIMITED COMPANY (IE) 2025-09-24 EP disclosed
US-20150344521-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES CYPRALIS LIMITED (GB) 2015-12-03 US disclosed
US-20150274774-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES CYPRALIS LIMITED (GB) 2015-10-01 US disclosed
US-9145441-B2 Macrocyclic inhibitors of flaviviridae viruses GILEAD SCIENCES, INC. (US) 2015-09-29 US disclosed
US-9090653-B2 Macrocyclic inhibitors of flaviviridae viruses GILEAD SCIENCES, INC. (US) 2015-07-28 US disclosed
US-8741834-B2 Dipeptoid prodrugs and the use thereof BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-06-03 US disclosed
US-20140030221-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES CYPRALIS LIMITED (GB) 2014-01-30 US disclosed
US-20110294719-A1 DIPEPTOID PRODRUGS AND THE USE THEREOF Bayer Schering Pharma 2011-12-01 US disclosed
EP-0519748-B1 Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme MERCK & CO INC (US) 1998-09-02 EP disclosed
US-5434248-A Peptidyl derivatives as inhibitors of interleukin-1β converting enzyme MERCK & CO., INC. (US) 1995-07-18 US disclosed
EP-0519748-A2 Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme MERCK & CO. INC. (US) 1992-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140030221-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES HAVCR2, ZC3HAV1, HCCS CTSK 1762/4885CTSS 1084/4885PSENEN 3107/4885
US-20150274774-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES HAVCR2, ZC3HAV1, HCCS CTSK 1762/4885CTSS 1084/4885PSENEN 3107/4885
US-12589101-B2 Cyclodextrin protein drug conjugates SSB, CHP1, IAPP CTSK 4224/4885CTSS 3258/4885PSENEN 1717/4885
US-20110294719-A1 DIPEPTOID PRODRUGS AND THE USE THEREOF DPP4, DPP3, DNPEP CTSK 3343/4885CTSS 4178/4885PSENEN 323/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR CTSK 2559/4885CTSS 2100/4885PSENEN 3227/4885
US-20260053943-A1 NANOCOMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE AND USE THEREOF CD47, PBK, CD4 CTSK 2555/4885CTSS 4393/4885PSENEN 2914/4885
US-20150344521-A1 MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES HAVCR2, ZC3HAV1, HCCS CTSK 1762/4885CTSS 1084/4885PSENEN 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.