SCHEMBL22371978

SCHEMBL22371978

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nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.63
CTSS P25774 3/20 0.63
PSENEN Q9NZ42 1/20 0.48
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA7 P43166 1/20 0.47
PREP P48147 1/20 0.45
CTSL P07711 2/20 0.44
CTSB P07858 2/20 0.44
TRPA1 O75762 1/20 0.44
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7345617 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL22371977 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL7018649 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL15671593 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL3087516 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL7345607 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL22371979 1.00 CTSK (0.63) CTSKCTSSPSENENCA2CA1
SCHEMBL59323 0.93 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL467994 0.93 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL256794 0.93 CTSK (0.61) CTSKCTSSCA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3716981-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS Viewpoint Therapeutics, Inc. (US) 2020-10-07 EP disclosed
US-20200276211-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS VIEWPOINT THERAPEUTICS INC (US) 2020-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200276211-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS CRYAB, PDE6C, CRYAA CTSK 708/4885CTSS 1157/4885PSENEN 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.