Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281288 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL16536004 | 0.85 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL16536963 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL16543633 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL16536117 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL27670765 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL16536006 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL16536196 | 0.81 | PDE4B (0.55) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL7294168 | 0.81 | CYP1A1 (0.53) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL7294180 | 0.81 | CYP1A1 (0.53) | KDM4EALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | claimed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |