Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294180 | 1.00 | CYP1A1 (0.53) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL7285807 | 0.81 | KDM4E (0.56) | PTGER4KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7294175 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL7283686 | 0.73 | CYP1A1 (0.58) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL7283674 | 0.73 | CYP1A1 (0.58) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL5501583 | 0.71 | NFE2L2 (0.81) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL5501588 | 0.71 | NFE2L2 (0.81) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL7281288 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL8864522 | 0.69 | NFE2L2 (0.72) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 | |
| SCHEMBL8864519 | 0.69 | NFE2L2 (0.72) | CYP1A1CYP1B1NFE2L2CYP19A1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | claimed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |