Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.63 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294349 | 0.94 | TBXAS1 (0.67) | TBXAS1MEN1KMT2AMAPK1NOS1 | |
| SCHEMBL15133511 | 0.88 | — | — | |
| SCHEMBL937596 | 0.80 | TBXAS1 (0.95) | TBXAS1 | |
| SCHEMBL9777196 | 0.80 | TBXAS1 (0.85) | TBXAS1HSD17B10 | |
| SCHEMBL762532 | 0.80 | TBXAS1 (0.63) | TBXAS1QPCTMEN1KMT2AATM | |
| SCHEMBL1679410 | 0.78 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL939851 | 0.78 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10247600 | 0.78 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL285054 | 0.78 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2533366 | 0.78 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023330-A1 | QUINAZOLINE DERIVATIVE | 石药集团中奇制药技术（石家庄）有限公司 | 2016-02-18 | — | — | WO | disclosed |
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |