Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.67 |
| ▸ | NOS1 | P29475 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285990 | 0.94 | TBXAS1 (0.63) | TBXAS1NOS1KMT2AMEN1MAPK1 | |
| SCHEMBL15133511 | 0.86 | — | — | |
| SCHEMBL22268942 | 0.84 | TBXAS1 (0.66) | TBXAS1NOS1LMNAKDM4EKMT2A | |
| SCHEMBL22268985 | 0.84 | TBXAS1 (0.66) | TBXAS1NOS1LMNAKDM4EKMT2A | |
| SCHEMBL22268813 | 0.84 | TBXAS1 (0.66) | TBXAS1NOS1LMNAKDM4EKMT2A | |
| SCHEMBL937596 | 0.83 | TBXAS1 (0.95) | TBXAS1 | |
| SCHEMBL1679410 | 0.81 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10247600 | 0.81 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2535103 | 0.81 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL939851 | 0.81 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |