Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435089 | 0.85 | RAB9A (0.60) | HTTRAB9ANPC1PKMALOX15 | |
| Benzene SCHEMBL7271816 | 0.83 | LMNA (0.56) | HTTFFAR2KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11770912 | 0.82 | ACE (0.61) | HTTRAB9ANPC1KMT2AMEN1 | |
| Benzene SCHEMBL7271414 | 0.82 | ACE (0.61) | HTTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL24767438 | 0.82 | HSD17B10 (0.59) | HTTRAB9ANPC1PKMALOX15 | |
| SCHEMBL18439983 | 0.81 | RAB9A (0.61) | HTTRAB9ANPC1PKMALOX15 | |
| SCHEMBL1911526 | 0.81 | HTT (0.67) | HTTRAB9ANPC1PKMALOX15 | |
| SCHEMBL3253290 | 0.80 | HTT (0.63) | HTTRAB9ANPC1PKMALOX15 | |
| SCHEMBL22939497 | 0.78 | HTT (0.61) | HTTRAB9ANPC1PKMALOX15 | |
| SCHEMBL1800442 | 0.78 | HTT (0.61) | HTTRAB9ANPC1PKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115997-A2 | Derivatives of omega mercaptopropanamides, and their homologues, process for their preparation, their use as medicines, compositions containing them and intermediates obtained | ROUSSEL-UCLAF (FR) | 1984-08-15 | — | — | EP | disclosed |