Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284745 | 0.94 | REN (0.61) | REN | |
| SCHEMBL7283881 | 0.93 | REN (0.60) | REN | |
| SCHEMBL7283775 | 0.92 | REN (0.59) | REN | |
| SCHEMBL7293569 | 0.92 | REN (0.59) | REN | |
| SCHEMBL7293194 | 0.91 | CTSL (0.52) | RENCTSLCTSBCTSS | |
| SCHEMBL7287419 | 0.90 | REN (0.60) | REN | |
| SCHEMBL9724084 | 0.89 | REN (0.55) | REN | |
| SCHEMBL7288827 | 0.89 | REN (0.59) | REN | |
| SCHEMBL9724073 | 0.89 | REN (0.52) | RENCTSLCTSBCTSS | |
| SCHEMBL9724076 | 0.86 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116835-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0372537-A2 | Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | disclosed |