Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294870 | 0.93 | SLC2A1 (0.70) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7274157 | 0.93 | HPGD (0.58) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7288312 | 0.93 | SLC2A1 (0.72) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7433595 | 0.93 | SLC2A1 (0.72) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7445759 | 0.93 | SLC2A1 (0.72) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7274466 | 0.92 | ALDH1A1 (0.59) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7442962 | 0.91 | SLC2A1 (0.70) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7293563 | 0.90 | SLC2A1 (0.65) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7294216 | 0.89 | SLC2A1 (0.69) | SLC2A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7294302 | 0.89 | SLC2A1 (0.64) | SLC2A1MEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |