SCHEMBL728615

SCHEMBL728615

O=C(O)c1c(O)c(O)c(C(=O)O)c2c1CC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
LDHA P00338 3/20 0.35
LDHB P07195 3/20 0.35
GLRA3 O75311 1/20 0.34
GLRB P48167 1/20 0.34
PTPN1 P18031 7/20 0.34
PTPRA P18433 2/20 0.34
PTPRC P08575 3/20 0.33
PTPN2 P17706 3/20 0.33
PTPRB P23467 2/20 0.33
PTPRE P23469 2/20 0.33
PTPN6 P29350 1/20 0.33
CYP1A2 P05177 1/20 0.33
TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5573410 0.89 PTPN1 (0.43) DPP4LDHALDHBPTPN1PTPRC
SCHEMBL3034094 0.84 CYP1A2 (0.38) DPP4CA12CA1CA2CA7
SCHEMBL7614679 0.83 LDHA (0.38) DPP4CA12CA1CA2CA7
SCHEMBL10338512 0.81 CYP1A2 (0.36) CA12CA1CA2CA7CA9
SCHEMBL1930355 0.81 CYP1A2 (0.36) CA12CA1CA2CA7CA9
SCHEMBL17504254 0.79 TNF (0.41) LDHALDHBGLRA3GLRBPTPN1
SCHEMBL1987618 0.79 CYP1A2 (0.35) CA12CA1CA2CA7CA9
SCHEMBL23164220 0.77 GLRA3 (0.48) DPP4CA12CA1CA2CA7
SCHEMBL7940169 0.76 PTPN1 (0.41) LDHALDHBPTPN1PTPRCPTPN2
SCHEMBL3332818 0.74 GLRA3 (0.46) DPP4CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4808844-B2 2011-11-02 JP claimed
EP-1310514-B1 A silane copolymer and process for preparing the same BARD INC C R (US) 2008-09-10 EP claimed
US-6908681-B2 Silane copolymer coatings C.R. BARD, INC. (US) 2005-06-21 US claimed
EP-1310514-A2 A silane copolymer and process for preparing the same C.R. Bard Inc. (US) 2003-05-14 EP claimed
EP-1129119-B1 SILANE COPOLYMER COATINGS BARD INC C R (US) 2003-04-02 EP claimed
US-20020128419-A1 Silane copolymer coatings TERRY RICHARD N (US) 2002-09-12 US claimed
US-6329488-B1 MEDICAL DEVICES, SUCH CATHETERS HAVING COATING C. R. BARD, INC. 2001-12-11 US claimed
EP-1129119-A2 SILANE COPOLYMER COATINGS C.R. Bard Inc. (US) 2001-09-05 EP claimed
WO-2000027897-A2 SILANE COPOLYMER COATINGS C.R. BARD, INC. (US) 2000-05-18 WO claimed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US claimed
US-11547116-B2 Metal oxide compounds and infusion into polymer compounds WINGFIELD WILLIAM (US) 2023-01-10 US disclosed
US-10687535-B2 Chelated metal oxide gel compositions AG TECH LLC (US) 2020-06-23 US disclosed
US-10442824-B2 Method for the production of a titanium containing catalyst, titanium containing catalyst, method for the production of polyester and polyester UHDE INVENTA-FISCHER GMBH (DE) 2019-10-15 US disclosed
EP-2173428-B1 FOLEY CATHETER HAVING STERILE BARRIER BARD INC C R (US) 2018-10-10 EP disclosed
EP-2765149-B1 METHOD FOR THE PRODUCTION OF A TITANIUM CONTAINING CATALYST, TITANIUM CONTAINING CATALYST, METHOD FOR THE PRODUCTION OF POLYESTER AND POLYESTER UHDE INVENTA FISCHER GMBH (DE) 2018-10-10 EP disclosed
WO-2000027897-A2 SILANE COPOLYMER COATINGS C.R. BARD, INC. (US) 2000-05-18 WO disclosed
EP-0598879-B1 PROCESS FOR THE PRODUCTION OF POLYESTER RESINS FOR FIBERS SINCO RICERCHE SPA (IT) 1998-08-19 EP disclosed
US-5569510-A FINAL POLYCONDENSATION OF POLYESTER MELT WITH A DIANHYDRIDE SINCO ENGINEERING S.P.A. (IT) 1996-10-29 US disclosed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US disclosed
US-5080798-A High Preformance Liquid Chromatography AMOCO CORPORATION (US) 1992-01-14 US disclosed