SCHEMBL7614679

SCHEMBL7614679

Cc1c(O)c(C(=O)O)c2c(c1C(=O)O)CC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.38
LDHB P07195 3/20 0.38
CYP3A4 P08684 4/20 0.33
ACHE P22303 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
MAPT P10636 3/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
SLC22A8 Q8TCC7 1/20 0.32
GPR35 Q9HC97 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
DPP4 P27487 1/20 0.31
POLB P06746 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728615 0.83 DPP4 (0.37) LDHALDHBGLRA3GLRBMAPT
SCHEMBL7577609 0.80 LDHA (0.46) LDHALDHBCYP3A4ACHEGLRA3
SCHEMBL5586337 0.76 POLB (0.41) LDHALDHBCYP3A4ACHEMAPT
SCHEMBL18677490 0.75 LDHA (0.48) LDHALDHBCYP3A4ACHEGLRA3
SCHEMBL27364369 0.75 LDHA (0.43) LDHALDHBCYP3A4ACHEGLRA3
SCHEMBL3034094 0.74 CYP1A2 (0.38) MAPTCYP1A2TSHRDPP4MEN1
SCHEMBL6603123 0.74 HTT (0.38) LDHALDHBCYP3A4ACHEMAPT
SCHEMBL5573410 0.73 PTPN1 (0.43) LDHALDHBMAPTTSHRDPP4
SCHEMBL21594816 0.72 LDHA (0.50) LDHALDHBCYP3A4ACHEGLRA3
SCHEMBL28582930 0.72 LDHA (0.45) LDHALDHBCYP3A4ACHEGLRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023369-B1 DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS EASTMAN CHEM CO (US) 2002-01-16 EP claimed