Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295690 | 0.94 | SLC2A1 (0.57) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7294302 | 0.93 | SLC2A1 (0.64) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7292845 | 0.92 | SLC2A1 (0.65) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7274466 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7286000 | 0.91 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7285826 | 0.90 | SLC2A1 (0.56) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7286147 | 0.90 | SLC2A1 (0.58) | ALDH1A1SLC2A1MEN1KMT2AMAPT | |
| SCHEMBL7293563 | 0.89 | SLC2A1 (0.65) | SLC2A1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL7294870 | 0.88 | SLC2A1 (0.70) | SLC2A1MEN1KMT2ASMN1; SMN2MTNR1A | |
| SCHEMBL7433595 | 0.87 | SLC2A1 (0.72) | SLC2A1MEN1KMT2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |