Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286167 | 0.94 | ALDH1A1 (0.55) | SLC2A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7274157 | 0.92 | HPGD (0.58) | SLC2A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7294870 | 0.91 | SLC2A1 (0.70) | SLC2A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL7288312 | 0.90 | SLC2A1 (0.72) | SLC2A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7433595 | 0.90 | SLC2A1 (0.72) | SLC2A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7445759 | 0.90 | SLC2A1 (0.72) | SLC2A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7292783 | 0.90 | SLC2A1 (0.58) | SLC2A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL7442962 | 0.89 | SLC2A1 (0.70) | SLC2A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL7285648 | 0.88 | SLC2A1 (0.64) | SLC2A1HPGDMEN1KMT2AMTNR1A | |
| SCHEMBL7296318 | 0.88 | SLC2A1 (0.64) | SLC2A1HDAC1HDAC6HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |