Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 16/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428294 | 0.94 | BACE1 (0.47) | BACE1RENCTSD | |
| SCHEMBL7287198 | 0.94 | BACE1 (0.46) | BACE1RENCTSD | |
| SCHEMBL7434424 | 0.93 | BACE1 (0.46) | BACE1RENCTSD | |
| SCHEMBL7295725 | 0.90 | REN (0.48) | BACE1REN | |
| SCHEMBL7293592 | 0.90 | REN (0.45) | BACE1RENCTSD | |
| SCHEMBL7287507 | 0.90 | REN (0.45) | BACE1RENCTSD | |
| SCHEMBL7287567 | 0.87 | REN (0.44) | REN | |
| SCHEMBL7427718 | 0.86 | REN (0.44) | BACE1REN | |
| SCHEMBL7279336 | 0.83 | REN (0.40) | BACE1RENCTSD | |
| SCHEMBL10416807 | 0.83 | REN (0.40) | BACE1RENMMP3CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | claimed |
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |