Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 17/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286310 | 0.94 | BACE1 (0.45) | BACE1RENCTSD | |
| SCHEMBL7287198 | 0.94 | BACE1 (0.46) | BACE1RENCTSD | |
| SCHEMBL7434424 | 0.94 | BACE1 (0.46) | BACE1RENCTSD | |
| SCHEMBL7295725 | 0.91 | REN (0.48) | BACE1REN | |
| SCHEMBL7293592 | 0.90 | REN (0.45) | BACE1RENCTSD | |
| SCHEMBL7287507 | 0.90 | REN (0.45) | BACE1RENCTSD | |
| SCHEMBL7287567 | 0.87 | REN (0.44) | REN | |
| SCHEMBL7286052 | 0.87 | BACE1 (0.48) | BACE1RENCTSD | |
| SCHEMBL7427718 | 0.86 | REN (0.44) | BACE1REN | |
| SCHEMBL7428494 | 0.86 | BACE1 (0.45) | BACE1RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | claimed |
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |