Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286414 | 1.00 | APLNR (0.49) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL7438047 | 0.99 | APLNR (0.50) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL7438062 | 0.99 | APLNR (0.50) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL7295827 | 0.92 | C5AR1 (0.53) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL7295836 | 0.92 | C5AR1 (0.53) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL11497533 | 0.90 | C5AR1 (0.47) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL11497532 | 0.90 | C5AR1 (0.47) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL30974024 | 0.82 | APLNR (0.52) | APLNRC5AR1OPRM1OPRK1CTSL | |
| SCHEMBL7296869 | 0.82 | OPRM1 (0.52) | OPRM1OPRK1 | |
| SCHEMBL7296864 | 0.82 | OPRM1 (0.52) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |