Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185806 | 0.76 | PTGER4 (0.33) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5382402 | 0.75 | MEN1 (0.35) | PTGER4PTGER3PTGER2CTSL | |
| SCHEMBL9575583 | 0.74 | IDO1 (0.37) | PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL9575838 | 0.74 | IDO1 (0.37) | PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL9450427 | 0.74 | IDO1 (0.37) | PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL10597079 | 0.74 | IDO1 (0.37) | PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL8901183 | 0.74 | IDO1 (0.34) | PTGER4PTGER3PTGER2TP53 | |
| SCHEMBL515453 | 0.74 | ADH1B (0.40) | PTGER4PTGER3PTGER2CTSL | |
| SCHEMBL9575433 | 0.71 | IDO1 (0.35) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6085440 | 0.71 | IDO1 (0.32) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297815-B1 | Fluorine containing renin inhibitors | PFIZER (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0297815-A2 | Fluorine containing renin inhibitors | PFIZER INC. (US) | 1989-01-04 | — | — | EP | disclosed |