Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL2778270 | 0.95 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propene SCHEMBL26630 | 0.95 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propene SCHEMBL2776876 | 0.95 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propene SCHEMBL2777932 | 0.95 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propene SCHEMBL6540791 | 0.93 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propylene Oxide SCHEMBL1905555 | 0.89 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Propane SCHEMBL29201 | 0.88 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Ethylene Glycol SCHEMBL5922943 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Ethylene Glycol SCHEMBL1094764 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Ethylene Glycol SCHEMBL8429233 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4744139-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7429636-B2 | Organohydrogensilicon compounds | DOW CORNING CORPORATION (US) | 2008-09-30 | — | — | US | claimed |