Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 2/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353406 | 0.96 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| SCHEMBL7288459 | 0.85 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| SCHEMBL6209756 | 0.83 | MGLL (0.68) | RAB9ANPC1SMN1; SMN2MGLLTSHR | |
| SCHEMBL29951102 | 0.83 | MGLL (0.68) | RAB9ANPC1SMN1; SMN2MGLLTSHR | |
| SCHEMBL2321762 | 0.82 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7286894 | 0.81 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| SCHEMBL2281889 | 0.81 | HPGD (0.50) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| 3-Phenylpropyl Phenylcarbamate SCHEMBL13625195 | 0.80 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| SCHEMBL7295364 | 0.78 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2RECQLMGLL | |
| SCHEMBL1952517 | 0.76 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2RECQLMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |