Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287141 | 1.00 | REN (0.47) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL9725854 | 0.87 | REN (0.47) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7293224 | 0.86 | REN (0.46) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL9725744 | 0.86 | REN (0.47) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7300500 | 0.86 | REN (0.61) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7300506 | 0.86 | REN (0.61) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7316942 | 0.84 | REN (0.50) | RENCTSLCTSB | |
| SCHEMBL9725827 | 0.84 | REN (0.45) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7305274 | 0.81 | REN (0.46) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7305280 | 0.81 | REN (0.46) | RENCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |