Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.74 |
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140482 | 0.91 | MEN1 (0.66) | SIGMAR1FAAHTSHR | |
| SCHEMBL3026419 | 0.85 | SIGMAR1 (0.74) | SIGMAR1FAAHTSHR | |
| SCHEMBL27564901 | 0.84 | SIGMAR1 (0.73) | SIGMAR1FAAH | |
| Hydrochloric Acid SCHEMBL7982333 | 0.84 | SIGMAR1 (0.97) | SIGMAR1FAAHTSHR | |
| SCHEMBL5064043 | 0.83 | ALDH1A1 (0.71) | SIGMAR1FAAHTSHR | |
| SCHEMBL7289040 | 0.82 | SIGMAR1 (0.69) | SIGMAR1FAAHTSHR | |
| SCHEMBL8268617 | 0.82 | SIGMAR1 (0.69) | SIGMAR1FAAH | |
| SCHEMBL7278874 | 0.81 | SIGMAR1 (0.67) | SIGMAR1FAAHTSHR | |
| SCHEMBL13149417 | 0.81 | MEN1 (0.68) | SIGMAR1FAAH | |
| SCHEMBL3134003 | 0.81 | SIGMAR1 (0.74) | SIGMAR1FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281598-A | Psychological disorders | AKZO N.V. (NL) | 1994-01-25 | — | — | US | disclosed |
| EP-0566189-A1 | Psychotropic piperazine derivative | AKZO N.V. (NL) | 1993-10-20 | — | — | EP | disclosed |