Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | S100B | P04271 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22199971 | 0.86 | CA9 (0.59) | POLBALDH1A1CA9CA12CA1 | |
| SCHEMBL13228866 | 0.81 | LPAR1 (0.47) | POLBCTDSP1ALDH1A1MAPK1CA9 | |
| SCHEMBL29906097 | 0.80 | ESR1 (0.55) | ALDH1A1CA9CA12CA1ESR1 | |
| SCHEMBL13460950 | 0.80 | ESR1 (0.55) | ALDH1A1CA9CA12CA1ESR1 | |
| SCHEMBL11246411 | 0.80 | POLB (0.77) | POLBTDP1CTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9277775 | 0.80 | ESR1 (0.43) | POLBS100BALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9156607 | 0.79 | ESR1 (0.42) | POLBS100BALDH1A1MAPK1CA9 | |
| SCHEMBL15493901 | 0.79 | CA12 (0.46) | POLBTDP1S100BALDH1A1MAPK1 | |
| SCHEMBL18470137 | 0.79 | POLB (0.63) | POLBTDP1CTDSP1S100BALDH1A1 | |
| SCHEMBL818923 | 0.78 | MAPK1 (0.49) | ALDH1A1SMN1; SMN2MAPK1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-6639042-B1 | Organic solvent soluble | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-10-28 | — | — | US | disclosed |