Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 12/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278238 | 0.91 | CTSK (0.43) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7267552 | 0.90 | CTSK (0.45) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7269350 | 0.87 | CTSK (0.40) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7269345 | 0.87 | CTSK (0.40) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7276776 | 0.87 | CTSS (0.41) | CTSSCTSKMMP9MMEACE | |
| SCHEMBL7269759 | 0.87 | CTSK (0.41) | CTSSCTSKMMP9MMEACE | |
| SCHEMBL7276785 | 0.87 | CTSS (0.41) | CTSSCTSKMMP9MMEACE | |
| SCHEMBL7278747 | 0.87 | CTSK (0.39) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7278741 | 0.87 | CTSK (0.39) | CTSSCTSKMMP9MMP2MMP8 | |
| SCHEMBL7267189 | 0.86 | CTSK (0.48) | CTSSCTSKMMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |