Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287458 | 0.82 | ALDH1A1 (0.42) | MAPTTP53SMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL7285051 | 0.79 | DDB1 (0.50) | MAPTTP53SMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL17634130 | 0.77 | MAPT (0.66) | MAPTTP53SMN1; SMN2CYBBNOX3 | |
| SCHEMBL17634166 | 0.75 | MEN1 (0.68) | MAPTTP53SMN1; SMN2CYBBNOX3 | |
| SCHEMBL839339 | 0.75 | DDB1 (0.47) | MAPTPARP1PARP2NPC1 | |
| SCHEMBL7289668 | 0.73 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1GAAMAPK1 | |
| SCHEMBL9876505 | 0.73 | HSD17B10 (0.73) | MAPTTP53SMN1; SMN2CYBBNOX3 | |
| SCHEMBL30923532 | 0.73 | HSD17B10 (0.73) | MAPTTP53SMN1; SMN2CYBBNOX3 | |
| SCHEMBL9206274 | 0.73 | HSD17B10 (0.73) | MAPTTP53SMN1; SMN2CYBBNOX3 | |
| SCHEMBL9206281 | 0.73 | HSD17B10 (0.73) | MAPTTP53SMN1; SMN2CYBBNOX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394101-B1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| US-5063225-A | Antiarrhythmia | ROUSSEL UCLAF (FR) | 1991-11-05 | — | — | US | disclosed |
| EP-0394101-A1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-10-24 | — | — | EP | disclosed |