Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287889 | 0.82 | MAPT (0.47) | ALDH1A1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL7285051 | 0.82 | DDB1 (0.50) | ALDH1A1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL9765801 | 0.81 | MAPT (0.43) | ALDH1A1MEN1KMT2AHSD17B10ALOX15 | |
| SCHEMBL7289668 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL10650323 | 0.75 | HSD17B10 (0.49) | ALDH1A1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL7296419 | 0.74 | DDB1 (0.55) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL7298642 | 0.74 | MEN1 (0.43) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL8905187 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL8853352 | 0.72 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL4495147 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394101-B1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| US-5063225-A | Antiarrhythmia | ROUSSEL UCLAF (FR) | 1991-11-05 | — | — | US | disclosed |
| EP-0394101-A1 | Benzothiazepine derivatives, process for their preparation and thereby obtained intermediates, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-10-24 | — | — | EP | disclosed |