Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690311 | 1.00 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| Acetic Acid SCHEMBL11102115 | 0.94 | RNPEP (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL17746783 | 0.85 | SLC15A1 (0.48) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL1920676 | 0.83 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL3686360 | 0.83 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL1896269 | 0.83 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL28323413 | 0.83 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL11101944 | 0.83 | CTSC (0.41) | CTSCRNPEPMETAP2METAP1ANPEP | |
| SCHEMBL10080417 | 0.82 | — | — | |
| SCHEMBL21135259 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050503-B1 | PHARMACOLOGICALLY ACTIVE PENTAPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | claimed |
| EP-0050503-A1 | Pharmacologically active pentapeptide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | claimed |
| WO-2018109496-A2 | UNNATURAL AMINO ACIDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-06-21 | — | — | WO | disclosed |
| WO-2018109496-A2 | UNNATURAL AMINO ACIDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-06-21 | — | — | WO | disclosed |
| US-20170101439-A1 | GAMMA-AA-PEPTIDE STAT3/DNA INHIBITORS AND METHODS OF USE | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-04-13 | — | — | US | disclosed |
| US-20120196933-A1 | MEXILETINE PRODRUGS | FRANKLIN RICHARD (GB) | 2012-08-02 | — | — | US | disclosed |
| WO-2012085586-A1 | MEXILETINE PRODRUGS | SHIRE, LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-5481026-A | ADDITION POLYMERIZABLE TO CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF RACEMIC MIXTURES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5357001-A | Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |
| EP-0220417-B1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF ALPHA-VINYL-ALPHA-AMINOCARBOXYLIC ACIDS | Degussa Aktiengesellschaft (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0220417-A1 | Process for the enantioselective preparation of alpha-vinyl-alpha-aminocarboxylic acids | Degussa Aktiengesellschaft (DE) | 1987-05-06 | — | — | EP | disclosed |
| EP-0137351-B1 | Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids | Degussa Aktiengesellschaft (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0137351-A2 | Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids | Degussa Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | disclosed |
| EP-0050503-B1 | PHARMACOLOGICALLY ACTIVE PENTAPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0050503-A1 | Pharmacologically active pentapeptide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| EP-0030848-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196933-A1 | MEXILETINE PRODRUGS | SLC16A1, MTPN, SLC16A3 | CTSC 520/4885RNPEP 1358/4885METAP2 341/4885 |
| US-20170101439-A1 | GAMMA-AA-PEPTIDE STAT3/DNA INHIBITORS AND METHODS OF USE | STAT3, JAK2, STAT1 | CTSC 2099/4885RNPEP 767/4885METAP2 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.