Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.56 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297903 | 0.96 | OXTR (0.58) | OXTRAVPR1AAVPR1B | |
| SCHEMBL7296349 | 0.92 | OXTR (0.62) | OXTR | |
| SCHEMBL7286950 | 0.91 | OXTR (0.62) | OXTR | |
| SCHEMBL7288884 | 0.90 | OXTR (0.61) | OXTRAVPR1AAVPR1B | |
| SCHEMBL7297556 | 0.90 | OXTR (0.61) | OXTRAVPR1AAVPR1B | |
| SCHEMBL7295366 | 0.89 | OXTR (0.64) | OXTRAVPR1A | |
| SCHEMBL7297843 | 0.89 | OXTR (0.66) | OXTR | |
| SCHEMBL7288276 | 0.89 | OXTR (0.73) | OXTRAVPR1A | |
| SCHEMBL7287499 | 0.89 | OXTR (0.57) | OXTRAVPR1AAVPR1B | |
| SCHEMBL7287400 | 0.88 | OXTR (0.59) | OXTRAVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |