SCHEMBL7296349

SCHEMBL7296349

COCCOc1cc(OC)ccc1C(=O)N1CCC(N2C(=O)CCc3ccccc32)CC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OXTR P30559 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7288884 0.96 OXTR (0.61) OXTR
SCHEMBL7286950 0.93 OXTR (0.62) OXTR
SCHEMBL7288164 0.92 OXTR (0.59) OXTR
SCHEMBL7297556 0.92 OXTR (0.61) OXTR
SCHEMBL7297843 0.91 OXTR (0.66) OXTR
SCHEMBL7288276 0.91 OXTR (0.73) OXTR
SCHEMBL7287400 0.91 OXTR (0.59) OXTR
SCHEMBL7297903 0.90 OXTR (0.58) OXTR
SCHEMBL7287499 0.89 OXTR (0.57) OXTR
SCHEMBL7286467 0.88 OXTR (0.60) OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5652247-A VASOPRESSIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD (JP) 1997-07-29 US disclosed
US-5436254-A Vaopressin antagonists OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1995-07-25 US disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed